From fb4eefdc7a9b7fe8a3e6de0fb9408695a61ea695 Mon Sep 17 00:00:00 2001 From: Erik Grobecker Date: Tue, 26 Nov 2024 08:13:14 +0100 Subject: [PATCH] Biologie am 25.11.2024 --- INDEX.md | 1 + ...{bio_2024-11-24.typ => bio_2024-11-21.typ} | 0 schule/bio/bio_2024-11-25.typ | 78 ++++++++++++++++++ schule/bio/pdfs/bio_2024-11-25.pdf | Bin 0 -> 45870 bytes 4 files changed, 79 insertions(+) rename schule/bio/{bio_2024-11-24.typ => bio_2024-11-21.typ} (100%) create mode 100644 schule/bio/bio_2024-11-25.typ create mode 100644 schule/bio/pdfs/bio_2024-11-25.pdf diff --git a/INDEX.md b/INDEX.md index 2d2f7ad..617f8d8 100644 --- a/INDEX.md +++ b/INDEX.md @@ -33,6 +33,7 @@ Hier wird nach Fächern sortiert und für diese einzelne Tabellen erstellt. | **Genetik:** Anfang der Epigenetik | 04.11.2024 | [hier](./schule/bio/pdfs/bio_2024-11-04.pdf) | | **Genetik:** genetische Modifikation bei Lachsen | 07.11.2024 | [hier](./schule/bio/pdfs/bio_2024-11-07.pdf) | | **Genetik:** CRISPR/Cas | 14.11.2024 | [hier](./schule/bio/pdfs/bio_2024-11-14.pdf) | +| **Genetik:** Letzte Stunde vor der Klausur → Gelektrophorese/PCR | 25.11.2024 | [hier](./schule/bio/pdfs/bio_2024-11-25.pdf) | ## Deutsch diff --git a/schule/bio/bio_2024-11-24.typ b/schule/bio/bio_2024-11-21.typ similarity index 100% rename from schule/bio/bio_2024-11-24.typ rename to schule/bio/bio_2024-11-21.typ diff --git a/schule/bio/bio_2024-11-25.typ b/schule/bio/bio_2024-11-25.typ new file mode 100644 index 0000000..31af3d8 --- /dev/null +++ b/schule/bio/bio_2024-11-25.typ @@ -0,0 +1,78 @@ +#import "@preview/grape-suite:1.0.0": exercise +#import exercise: project + +#set text(lang: "de") + +#show: project.with( + title: [Letzte Stunde vor der Klausur], + seminar: [Biologie Q2], + show-outline: true, + author: "Erik Grobecker", + date: datetime(day: 25, month: 11, year: 2024), + show-solutions: false +) + +#show math.equation: set text(font: "New Computer Modern") //Wird für Mathe bei Grape-Suite gebraucht + +#show "->": sym.arrow +#show "=>": sym.arrow.double + += Film --- Gelektrophorese & PCR + +== PCR + +=== Definition/Zweck + +Wird Polymerase-Kettenreaktion ausgeschrieben\ +Hiermit kann man aus wenig DNA, viel DNA bauen und bestimmte Sequenzen herausschneiden + +Multiplikation bestimmter DNA-Sequenzen + +=== Bestandteile + +- GEN +- DNA-Polymerase (muss hitzebeständig sein -> tak-Polymerase) +- Nucleotide +- Pufferlösung (hält ph-Wert stabil) +- Thermocycler +- Basenpaare + - nach _Denaturierung_: Matrizen +- Primer + +=== Schritte + ++ Denaturierung + - DNA-Doppelhelix wird durch Hitze gespalten (Wasserstoffbrücken werden getrennt) ++ Hybridiesierung + - Primer setzt an Basen vor der Sequenz an -> diese hält zuerst bis zum Ende der DNA an\ + #h(1em) #sym.arrow.curve Sequenz ist von _vor Beginn der zu-kopierenden-Sequenz an und hört nicht auf_ + // #h(1em) #sym.arrow.curve dies geschieht auch mit der antiparallelen DNA-Sequenz\ + // #h(1em) #sym.arrow.curve ++ Polymerisation + - DNA-Sequenz wird kopiert -> dies hält vom Anfang der Sequenz bis Ende der DNA an & geschieht mit antiparallelen Sequenz\ + - In der _zweiten Iteration_ tauschen Primer die Rollen -> *passende DNA-Sequenz wird kopiert* => erst in der _zweiten Iteration_ erhält man die richtige Sequenz + +Die Schritte verlaufen in mehreren Iteration, wobei erst nach der zweiten brauchbare Ergebnisse erfolgen. + +== Gelektrophorese + +Einheit von Fragmentlängen -> bp -> Basenpaare\ +kann für viele verschiedene Ziele verwendet werden (wie um bestimmt-große Bestandteile zu finden, etc.) + +== RFLP +(Restriktionsfragment-Längenpolymorphismus) + +sind bei jedem Menschen verschieden -> Menschen können hiermit identifiziert werden + +#pagebreak() + += für die Klausur + +- PCR, Gelektrophorese +- Genregulation + - RNA-Interferenz + - Prokaryoten(sämtliche Ebenen)/Eukaryoten +- Epigenetik + - CRISPR/Cas + - Regulation +- Stammbaumanalyse diff --git a/schule/bio/pdfs/bio_2024-11-25.pdf b/schule/bio/pdfs/bio_2024-11-25.pdf new file 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